Major Methods Of Peptide Bond Formation The Peptides Analysis Synthesis Biology

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Major Methods of Peptide Bond Formation : The Peptides Analysis, Synthesis, Biology

Science

Author - Erhard Gross, Johannes Meienhofer
Publisher - Elsevier
Pages - 454
ISBN - 1483217965


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Detail - The Peptides: Analysis, Synthesis, Biology, Volume 1: Major Methods of Peptide Bond Formation provides comprehensive and critical reviews of important developments in three major areas of peptide research—analysis, synthesis, and biology. This book discusses the nature of the peptide bond, coupling between amino acid residues, and catalysis of active ester reactions. The formation of hydrazides, reactions of carbodiimides with amines, and mixed carbonic anhydride method of peptide synthesis are also elaborated. This publication likewise covers the control of racemization during peptide synthesis, strategies for minimizing racemization during amide-forming steps, and assays for chiral purity. This volume is suitable for students, specialists, and scientists from a broad range of disciplines concerned with peptides.

The Peptides: Chemistry, biology, and medicine of neurohypophyseal hormones and their analogs :

Science

Author - Sidney Udenfriend
Publisher - Academic Pr
Pages - 370
ISBN -


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Chemical Approaches to the Synthesis of Peptides and Proteins :

Medical

Author - Paul Lloyd-Williams, Fernando Albericio, Ernest Giralt
Publisher - CRC Press
Pages - 304
ISBN - 9780849391422


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Detail - Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.

The Peptides: Major methods of peptide bond formation :

Peptides

Author - Erhard Gross, Johannes Meienhofer
Publisher -
Pages -
ISBN -


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The Peptides Analysis, Synthesis, Biology : Modern Techniques of Conformational Structural, and Configurational Analysis

Science

Author - Erhard Gross
Publisher - Elsevier
Pages - 330
ISBN - 0323155634


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Detail - The Peptides: Analysis, Synthesis, Biology: Volume 4: Modern Techniques of Conformational, Structural, and Configurational Analysis is an open-ended treatise that provides comprehensive and critical reviews of important developments in all areas of peptide research including analysis, synthesis, and biology. X-ray structure studies, amino acid analysis, and chiroptical analysis of configuration are discussed, along with solid-phase sequencing and ultramicroanalysis with the aid of fluorescence. This volume is comprised of six chapters and begins with an account of crystal structure analysis on molecules containing 2-12 peptide units, focusing on the variety of intramolecular hydrogen bonds, cis peptide units, and multiple conformation. Conformational changes upon complexation with metal ions are considered, together with the inclusion of solvents as integral parts of a molecular structure. The following chapters explore the conformations of insulin, glucagon, pancreatic polypeptide and related molecules, as well as the molecular biology of these hormones based on crystal structures; the usefulness of chiroptical techniques for determining the absolute configuration of amino acids and small peptides; and ultramicroanalysis of peptides and proteins by high performance liquid chromatography and fluorescence detection. The final chapter looks at the status and future potential of solid-phase sequencing. This book is intended as a reference for specialists, a guide for the novice, and a forum for investigators concerned with research on peptides and proteins.

Opioid Peptides: Biology, Chemistry, and Genetics : The Peptides: Analysis, Synthesis, Biology

Science

Author - Sidney Udenfriend, Johannes Meienhofer
Publisher - Elsevier
Pages - 446
ISBN - 148321799X


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Detail - The Peptides: Analysis, Synthesis, Biology, Volume 6: Opioid Peptides: Biology, Chemistry, and Genetics presents a biological topic of peptide research. This book is divided into nine chapters. Chapter 1 reviews the opioid peptide precursors and their genes. The proenkephalin and products of its processing are discussed in Chapter 2. In Chapter 3, the role of pro-opiomelanocortin (POMC) as a protein at the interface of the endocrine and nervous systems is examined. Chapter 4 provides a comprehensive account of the biology and chemistry of the dynorphin peptides. The opioid receptors are described in Chapter 5. Chapter 6 evaluates the structure-activity relationships of ?-endorphin, while Chapter 7 considers the conformational analysis of enkephalins and conformation-activity relationships. The structure-activity relationships among enkephalin peptides are elaborated in Chapter 8. The last chapter is devoted to the clinical significance of opioid peptides in humans. This publication is a good reference for biologists, specialists, and researchers concerned with peptides and proteins.

Conformation in Biology and Drug Design : The Peptides: Analysis, Synthesis, Biology

Science

Author - Sidney Udenfriend, Johannes Meienhofer, Victor J. Hruby
Publisher - Elsevier
Pages - 516
ISBN - 1483218007


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Detail - The Peptides: Analysis, Synthesis, Biology, Volume 7: Conformation in Biology and Drug Design focuses on the analysis of peptides, emphasizing the use of physical methods in peptide conformational analysis and the relationship of conformational properties of peptides to biological properties. This book consists of nine chapters. Chapter 1 provides a brief overview of the perspective on the application of physical methods to peptide conformational analysis. The use of circular dichroism (CD) spectroscopy to examine the conformational properties of peptides in solution is elaborated in Chapter 2, while the use of fluorescence spectroscopy to examine the special relationships of aromatic side-chain groups to one another is discussed in Chapter 3. In Chapter 4, the use of various theoretical methods to calculate the conformations of peptides is described. The methods used to stimulate peptide conformations and dynamics are outlined in Chapter 5. The last four chapters examine various aspects of the use of nuclear magnetic resonance (NMR) in peptide conformational analysis. This volume is suitable for biologists, specialists, and researchers interested in peptides and proteins.

Neuropeptides and Behavior: CNS effects of ACTH, MSH, and opioid peptides :

Medical

Author - David de Wied, Willem Hendrik Gispen, Tj. B. van Wimersma Greidanus
Publisher -
Pages - 440
ISBN -


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Burger's Medicinal Chemistry and Drug Discovery, Autocoids, Diagnostics, and Drugs from New Biology :

Medical

Author - Alfred Burger, Donald J. Abraham
Publisher - Wiley-Interscience
Pages - 724
ISBN -


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Detail - Offers access via basic and advanced search engines to broad coverage of the field of medicinal chemistry and drug discovery for medicinal chemists, biologists, pharmacologists and molecular biologists.

New Technical Books :

Engineering

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Encyclopedia of Molecular Biology and Molecular Medicine, Mass Spectrometry High Speed DNA Fragment Sizing to Plasma Lipoproteins :

Science

Author - Robert A. Meyers
Publisher - Wiley-Blackwell
Pages - 509
ISBN - 9783527284740


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Detail - This six volume Encyclopedia is the most comprehensive, detailed treatment of molecular biology and molecular medicine available today! The Encyclopedia provides a single-source library of molecular genetics and the molecular basis of life, with a focus on molecular medicine. Genetic screening, gene therapy, structural biology, and the technology and findings of the Human Genome Project are discussed in detail. The articles that comprise the set are designed as self-contained treatments. Each of the nearly 300 articles begins with an outline and a key word section which includes definitions. These features assist the scientist or student who is unfamiliar with a specific subject area. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, these definitions enable readers to understand articles without referring to a dictionary, textbook, or other reference.

The Peptides : Analysis, Synthesis, Biology

Science

Author - Erhard Gross
Publisher - Academic Pr
Pages - 508
ISBN - 9780123042057


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